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Dr. Anthony Jay on Decoding your DNA, Avoiding Male Feminization, and Epigenetics

Dr. Anthony Jay- Peak Human Podcast


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Hey everyone out there in podcast land, I'm Brian Sanders, and we’re back for another great episode. I had the pleasure of speaking with Dr. Anthony Jay this week. He’s probably best known for his book Estrogeneration where he explores how all the nasty xenoestrogens creep into our body through plastics, food like soy, personal care products, sunscreen, the water, etc. This is important stuff because you may think it doesn’t affect you, but it does, and you just don’t realize it. You don’t have to go crazy over this stuff, but it’s best to minimize your exposure.

What was really cool for me is that I got to talk to him before and after the show and realized what a great wealth of knowledge he has on so many subjects - which is also very apparent throughout the episode. We could have talked all day, but we cut ourselves off at 2 solid hours of hot nutrition talk.

Dr. Jay earned his Ph.D. in Biochemistry from Boston University School of Medicine, researching fats, hormones, and cholesterol. He’s currently at the Mayo Clinic in Rochester, Minnesota researching stem cells, epigenetics, and infrared light. He also does DNA consulting which I’m going to do with him in the near future.

So now for a huge announcement - the SAPIEN show is finally here! I haven’t mentioned it much, but it’s been in the works for a while. It’s recorded on video and audio at SAPIEN headquarters at Evolve Healthcare in Woodland Hills, California with in-person guests.

My co-host is the one and only Dr. Gary Shlifer who was a recent Peak Human guest. By far the most positive feedback of any episode. Go back and listen if you’d like (it’s episode 48) or just jump in and start with the Sapien podcast that is launching today!

So I’d suggest pausing this episode and subscribing now before you forget. Go ahead, I’ll wait. Just look up Sapien in any podcast app or on youtube. The podcast version has higher quality audio and the youtube version has our smiling faces! We already have a bunch of great episodes in the bag, including one where Dr. Paul Saladino and Dr. Gary get in a small war. It got awkward after that one.

My other co-host is Yaniv Fituci, the producer of Food Lies and co-founder of http://Attack.Media He produces shows for Disney, Sony, Nintendo and all that other Hollywood stuff. He’ll be coming in and out and bringing his awesome perspective into the mix.

So I’ll keep it quick this week on how to support this show, myself, and all things Sapien. My main venture is the Sapien Organization which can be found at which includes the Food Lies film, Nose to Tail grass finished meat, this podcast, and even the long term vision of changing the way we farm with the Sapien Movement. You can find out more about the Sapien Diet there which people have been asking about. I posted my before and after picture on instagram, facebook, and twitter to show what happens when you eat densely and move intensely and live a Sapien Lifestyle, which is how us modern homo sapiens in 2019 should be living. I swear it’s the easiest thing to do once you understand what to do and why you’re doing it. I eat the most delicious meals I can imagine until I’m full, never worry about calories or macros, then go work out for 17 minutes most weekdays… and this helped me transform my body and my life.

So start eating densely with all the grass finished meat on support this podcast so I can keep doing it at preorder the film so we can finish it - the more funds we have, the sooner it will come out. You can click through to the Indiegogo at and subscribe to the new Sapien show on any podcast app and the Food Lies YouTube channel.

Without further ado, please welcome the superb Dr. Anthony Jay.


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  • Dr. Anthony Jay is currently a researcher at the esteemed Mayo Clinic

  • He received his Phd at Boston University School of Medical in Biochemistry

  • Anthony’s definition of cholesterol and why it is absolutely essential

  • Why dietary cholesterol does not directly affect your blood cholesterol in a harmful way

  • How harmful exposure from estrogen is all around you whether it be everyday use products, your environment, diet or water supply

  • Fake estrogen (man-made chemicals) are harming you in products you would never expect

  • Why scientists, researchers, and governmental standards tend to ignore the negative effects of these everyday products and how they manage to stay on shelves

  • Explanation of how the problem lies with the slow buildup of these artificial estrogens in the body long term

  • How artificial estrogens alter sex hormones and can lead to male feminization

  • How Epigenetics work and instances it has been shown in history

  • You can read more about one of the first instances of Epigenetics here:

  • How methylation changes creates physical marks on DNA which lead to increases in DNA mutations and epigenetic alterations

  • How Atrazine, a widely used herbicide in North American agriculture (but illegal in Europe) is harming current and future generations

  • How estrogen directly influences PPAR-gamma (Peroxisome Proliferator-Activated Receptor Gamma) to store more fat

  • How estrogen affects SHBG (Sex Hormone Binding Globulin) and leads to lower testosterone

  • Why 4-Methylbenzylidene-camphor is being outlawed in Hawaii, Australis, New Zealand, Philippines, and the Caribbeans

  • How xenoestrogen compounds are even being found in polar bears in northern Alaska

  • Why Dr. Anthony Jay stopped using sea salt due to microplastics

  • How a pristine mountain lake in Switzerland with little to no human contact had its male fish somehow becoming female

  • Atrazine in even relatively low doses compared to US agriculture can still lead to male frogs to become female

  • How religious dogmatism in scientific community leads to little or no discourse about these types of issues

  • What Dr. Anthony Jay’s power rankings of dangerous xenoestrogens are

  • Check out what everyday products he uses and feels safe about at:

  • Learning about your genetic predispositions and how to cater your diet, supplements, and lifestyle to best fit your genetics is an effective way to live a healthier, longer life

  • How analyzes your genetics and allows you to get it looked at by professionals such as Dr. Anthony Jay to customize your own diet and supplementation

  • Iodine and Vitamin D are essential

  • The importance of cycling in and out of ketosis and being able to get fat adapted/metabolic flexibility

  • Reasoning behind intermittent fasting

  • Developing a foundation of strength - the big 6: squat, deadlift, bench, row, pull-down, overhead press

  • Why there is no such thing as a perfect diet for everybody

  • How to optimize sleep and why it's important

  • What flavonoids are and why he suggests them for most people

  • How you can optimize your testosterone

  • Heavy metal exposure can lead to testosterone to drop

  • How having too much of essential micronutrients can drop testosterone

  • Why you should avoid BPA, BPS, BPF and phthalates

  • If you want to learn more go check out his book “Estrogeneration: How Estrogenics are Making You Fat, Sick and Infertile”

  • Find him at


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1 Comment

Feb 06, 2020

This had the potential to be a great podcast. I'm not sure if it was a problem with the recording equipment or what, but there was way too much talking over each other. I finally gave up in frustration. But, I'm grateful for learning about Anthony.

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